Micromechanics of human mitotic chromosomes
نویسندگان
چکیده
منابع مشابه
Higher-order structure of human mitotic chromosomes.
From observations on the partial disintegration of isolated human metaphase chromosomes we propose that human metaphase chromatids have a rather simple organization based on the folding and coiling of a long, regular, hollow cylindrical structure with a diameter of about 4000 A. This cylindrical structure, the unit fiber, is postulated to be a super-solenoid formed by the coiling of a 300 A sol...
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Cyclin B1-CDK1 activity is essential for mitotic entry, but questions remain regarding how the activity of this kinase is spatially regulated. Previous studies showed that the cyclin B1 subunit localizes to several compartments of a mitotic cell, including the centrosomes, mitotic spindle, kinetochores and chromosomes via distinct sequence elements. Mitotic chromosome association occurs through...
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ژورنال
عنوان ژورنال: Physical Biology
سال: 2011
ISSN: 1478-3975
DOI: 10.1088/1478-3975/8/1/015003